- People with a defined clinical genetics question after counseling
- Research participants who understand uncertainty and privacy
- People prepared for incidental findings and possible confirmatory testing
TEST PASSPORT · REVIEWED JULY 2026
Whole genome + polygenic risk
A large data file with selective clinical value—not a complete biological forecast.Whole-genome sequencing can detect many variant types; polygenic scores combine many common variants. Clinical utility, portability across ancestry groups and actionability remain uneven.

HOW TO USE THIS PAGE
Decide whether this test deserves a place in your plan.
- 01Confirm the question
Be clear about what decision the result would change before ordering.
- 02Check fit and preparation
Review who it helps, who should pause and how to protect the quality of the signal.
- 03Plan the response
Know what you will do with a normal, abnormal or unclear result.
01 / WHO SHOULD TAKE IT
Fit the test to
the person.
Testing is useful when the result can change a real decision. These are educational selection criteria, not a diagnosis or personal order.- Replacing guideline-based screening
- Using a consumer longevity score to start medications
- Anyone who has not reviewed data retention and family implications
02 / SIGNAL VS. STORY
What it tells you.
What it cannot.
Variants detectable by the platform and pipeline
Selected monogenic findings when analyzed under clinical standards
Relative polygenic risk within a defined reference population
A genome does not measure current health or guarantee outcomes
Polygenic performance can vary across ancestry
Interpretation changes and false positives require confirmation
03 / MARKERS + RANGES
Read the panel
without chasing flags.
The report should show its own method, units and laboratory reference interval. Clinical decision thresholds may be different from a lab interval. We do not invent a universal “optimal” range where authoritative guidance does not support one.Use the laboratory unit and method, then interpret with symptoms, trend and the decision this marker can change.
Use the laboratory unit and method, then interpret with symptoms, trend and the decision this marker can change.
Use the laboratory unit and method, then interpret with symptoms, trend and the decision this marker can change.
Use the laboratory unit and method, then interpret with symptoms, trend and the decision this marker can change.
Use the laboratory unit and method, then interpret with symptoms, trend and the decision this marker can change.
The correct range is personal context—not pink versus blue numbers.
Where biology differs, we call it out. Clinical interpretation should also reflect organs present, hormone therapy, pregnancy, age, medications and health history.
Chromosomal sex, pregnancy and organ-specific screening are not replaced by genomic risk estimates.
Chromosomal sex and organ-specific screening are not replaced by genomic risk estimates.
04 / PREPARATION
Protect the quality
of the signal.
The best assay cannot rescue the wrong timing, wrong specimen or wrong question. Follow the ordering clinician and laboratory instructions when they differ from this general guide.Name the decision the test could change before ordering.
Review incidental findings, family implications, data sale, research use and deletion.
Plan to confirm medical findings in a clinical laboratory.
05 / AFTER THE RESULT
Turn the number
into a next step.
- 01
Confirm actionable findings clinically
- 02
Keep established screening on schedule
- 03
Use a genetics professional for high-impact results
Do not delay evaluation of symptoms because of a low genetic score
Use mental-health support if unexpected findings cause major distress
06 / MODERN BIO SELECT
Built for a responsible purchase path.
We will not rank consumer genome products until their methods, privacy and action pathways meet the standard.Whole genome + polygenic risk
- Future format
- Future counseling-first research pathway
- Price position
- Not currently shortlisted
- Before checkout
- Eligibility · method · privacy · total cost · interpretation · abnormal-result routing
07 / SCIENTIFIC FOUNDATION