The Modern Bio Baseline
CBC · CMP · A1c · core lipids · ApoB · Lp(a) · blood pressure
Partner build in progressA TEST SHOULD CHANGE A DECISION
From a $20 blood count to advanced imaging and genetics, this is a practical map of the tests people are offered—who they fit, how to prepare, what the result can and cannot tell you, and where the evidence says “not yet.”
Explore 32 test passports ↓


HOW TO USE THIS PAGE
Baseline, symptom, prevention, performance, treatment monitoring or an emerging test.
Check who it fits, preparation, limits, total cost and what happens after the result.
Use your history, medications and prior results when you discuss the test with a practitioner.
01 / CHOOSE BY DECISION
You are generally well and want the minimum useful health snapshot.
CBC · CMP · cardiometabolic risk · blood pressureEnter this lane ↗02Explain a symptomFatigue, palpitations, GI symptoms, poor sleep or another persistent concern.
History first · targeted tests · red-flag routingEnter this lane ↗03Refine preventionYour heart, bone, cancer or inherited-risk decision is uncertain.
Risk calculator · selective biomarkers · imaging only if decisiveEnter this lane ↗04Measure performanceYou will use the result to change training, nutrition or recovery.
VO₂/CPET · DXA · RMR · strength and functionEnter this lane ↗05Monitor treatmentA medicine, condition or therapy has a defined safety or response marker.
Correct method · useful interval · stop and escalation rulesEnter this lane ↗06Evaluate an emerging testYou are considering microbiome, genome or multi-cancer testing.
Clinical utility · false positives · privacy · follow-up burdenEnter this lane ↗02 / SEARCH THE COMPLETE LAB
32 test passports
Medical and source review updated July 2026A CBC can surface patterns consistent with anemia, infection, inflammation or platelet problems. It is a context test: an out-of-range cell count is a clue, not a diagnosis.
The CMP groups 14 common measurements. It can reveal patterns that deserve follow-up, but its liver and kidney values are not complete organ ‘health scores.’
A standard lipid panel remains useful. ApoB estimates the number of atherogenic particles; Lp(a) is largely inherited and is generally measured at least once in adulthood under current U.S. guidance.
Fasting glucose and A1c are established diabetes tests. Fasting insulin can add metabolic context, but no single universal insulin cutoff diagnoses insulin resistance.
hs-CRP can be a cardiovascular risk enhancer, but it rises with infection, injury, dental disease, obesity and hard exercise. The number never identifies the source on its own.
TSH is commonly the first test, often paired or reflexed to free T4. Antibodies and other measures answer narrower questions; a giant panel is not automatically better.
Ferritin is central but also rises with inflammation. Hemoglobin, serum iron, transferrin/TIBC and transferrin saturation help distinguish common patterns.
Vitamin B12 and folate relate to blood and neurologic function; methylmalonic acid can clarify B12 status. Vitamin D testing is valuable for selected risk and treatment contexts, not a universal monthly score.
Testosterone, estradiol, SHBG, LH, FSH and prolactin answer different questions. Random mega-panels create noise; a staged evaluation is more defensible.
Creatinine-based eGFR estimates filtration; urine albumin-to-creatinine ratio detects albumin leakage. Trends and persistence matter more than one isolated result.
Validated upper-arm home monitors and 24-hour ambulatory monitoring can identify sustained, white-coat or masked hypertension patterns.
A 12-lead ECG is a moment-in-time clinical test. Holter, patch and event monitors extend the window; consumer wearables can capture clues but do not replace diagnosis.
A CAC score can reclassify risk in selected adults. It uses radiation, sees calcified rather than all plaque and is not a universal annual biohacking scan.
An echocardiogram evaluates chambers, valves, pumping and selected pressure estimates. It is powerful when indicated, but not a blanket screening scan for everyone.
Central DXA is the clinical standard for bone mineral density. Some facilities add body-composition estimates, which are useful when repeated on the same machine under similar conditions.
A performance VO₂ test estimates aerobic capacity. Full clinical CPET adds ECG, gas exchange and symptoms to help evaluate unexplained exercise limitation.
Indirect calorimetry estimates resting energy expenditure from oxygen and carbon dioxide exchange. It can guide nutrition planning, but daily needs still change with movement, training and adaptation.
Grip dynamometry, sit-to-stand, gait speed and balance tests can track function. Technique and reference population matter, and a single score is never a diagnosis.
HSAT can diagnose obstructive sleep apnea in uncomplicated adults with signs and symptoms suggesting moderate-to-severe risk. Negative or inconclusive results may require in-lab polysomnography.
Polysomnography records brain activity, eyes, muscles, airflow, effort, oxygen, heart rhythm and more. It can evaluate sleep apnea and selected movement, behavior or hypersomnolence disorders.
Targeted panels can identify inherited variants that alter surveillance or family testing. Pre- and post-test counseling matter because uncertain and incidental findings are common.
PGx can be actionable for specific gene–drug pairs. FDA-cleared consumer reports cover limited claims; results should be confirmed and interpreted with the prescriber and medication history.
Whole-genome sequencing can detect many variant types; polygenic scores combine many common variants. Clinical utility, portability across ancestry groups and actionability remain uneven.
GI testing works when it answers a defined question. A clinician may use celiac serology, H. pylori testing, fecal calprotectin, pathogen testing or other targeted studies—never one universal gut panel.
Sequencing can describe organisms in a stool sample, but there is no validated universal ‘optimal microbiome.’ Cross-company scores and supplement recommendations are not interchangeable.
Skin-prick and serum specific-IgE tests identify sensitization. Clinical allergy requires the history to match; supervised oral food challenge may be needed for diagnosis.
Food-specific IgG often reflects exposure or tolerance, not disease. Major allergy organizations recommend against using these panels to diagnose food allergy or intolerance.
Blood lead testing is the standard exposure assessment for lead. Other metals require a specific source, timing and test; ‘provoked urine’ detox testing can mislead.
Established screening includes different tests for colorectal, breast, cervical and lung cancer and other risk-based pathways. No single age or bundle fits everyone.
MCD tests look for signals such as cancer-derived DNA across multiple cancers. They are being studied; none should replace established screening, and a positive result is not a diagnosis.
AMH and antral follicle count can help predict response to ovarian stimulation. They are poor stand-alone ‘fertility tests’ and do not measure egg quality.
Semen parameters vary between samples. A proper fertility evaluation uses standardized collection, laboratory methods, history and often a repeat—not one app-based score.
03 / BUILT FOR RESPONSIBLE COMMERCE
CBC · CMP · A1c · core lipids · ApoB · Lp(a) · blood pressure
Partner build in progressAdvanced lipids · glucose context · kidney risk · blood pressure · optional CAC routing
Partner build in progressStaged thyroid, iron, B12/folate/D and sex-hormone testing—not a random mega-panel
Clinician pathwayDXA · VO₂/CPET · resting metabolism · strength and function
Facility network plannedEligibility screen · home study · physician interpretation · treatment routing
Clinical partner plannedFuture test purchases may generate revenue. Commission will never determine whether a test is included, its evidence label or its position. “Do not sell” means exactly that.
04 / THE TEST QUALITY GATE
What exact action can a positive, negative or borderline result change?
Who benefits—and who is likely to be harmed or misled?
What specimen, assay, accreditation and quality controls are used?
Can users collect or prepare correctly without corrupting the result?
Are reference intervals, clinical thresholds and sex/life-stage context kept distinct?
Who owns confirmation, urgent findings and treatment referral?
Can the customer understand storage, sharing, research use and deletion?
Is the full price—including repeat and downstream work—visible before purchase?
READ THE RESULT LIKE A CLINICIAN
Fasting, hydration, illness, exercise, collection and medication timing can change a result.
A laboratory interval describes a population. A clinical threshold guides a decision. An internet “optimal” range may do neither.
Unexpected, high-impact results often deserve repeat or confirmatory testing with the right method.
Symptoms, history, anatomy, hormones, pregnancy, medicines and trend remain part of every interpretation.
THE MODERN BIO BRIEF